Basic Information
ID: ALA5124932
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against human HFF cells infected with VZV Ellen virus assessed as reduction in cell viability by cell titer-glo assay to EC50 for antiviral activity against VZV Ellen infected in HFF cells assessed as inhibition of virus-induced cytopathic effect measured after 14 days
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA5120909
Selectivity index, ratio of CC50 for cytotoxicity against human HFF cells infected with VZV Ellen virus assessed as reduction in cell viability by cell titer-glo assay to EC50 for antiviral activity against VZV Ellen infected in HFF cells assessed as inhibition of virus-induced cytopathic effect measured after 14 days: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5124932
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 255.23 | -1.97 | -1.97 |
| 225.21 | -1.33 | -1.33 |
| 404.40 | -1.66 | -1.66 |
| 428.43 | -1.08 | -1.08 |
| 419.42 | -1.64 | -1.64 |
| 444.43 | -1.78 | -1.78 |
| 405.39 | -1.95 | -1.95 |