Basic Information
ID: ALA5124936
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for anti-HIV activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA5120909
Selectivity index, ratio of CC50 for cytotoxicity against human MT4 cells assessed as reduction in cell viability by MTT assay to EC50 for anti-HIV activity against wild type HIV-1 IIIB infected in human MT4 cells assessed as inhibition of HIV-induced cytopathic effect measured after 5 days by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5124936
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.26 | -0.59 | -0.59 |
| 404.40 | -1.66 | -1.66 |
| 409.42 | -1.25 | -1.25 |
| 428.43 | -1.08 | -1.08 |
| 419.42 | -1.64 | -1.64 |
| 444.43 | -1.78 | -1.78 |
| 434.43 | -1.40 | -1.40 |
| 405.39 | -1.95 | -1.95 |
| 418.44 | -0.69 | -0.69 |
| 394.41 | -1.27 | -1.27 |
| 395.39 | -1.56 | -1.56 |