Basic Information
ID: ALA5125407
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged TAK1 (1 to 303 residues)/TAB1 (437 to end residues) expressed in baculovirus infected Sf9 insect cells using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition and measured after 45 mins by kinase-glo luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Document: ALA5120924
Inhibition of recombinant human N-terminal GST-tagged TAK1 (1 to 303 residues)/TAB1 (437 to end residues) expressed in baculovirus infected Sf9 insect cells using myelin basic protein as substrate preincubated for 10 mins followed by ATP addition and measured after 45 mins by kinase-glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5125407
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.38 | 1.03 | 1.03 |
| 494.45 | 2.26 | 2.26 |
| 418.40 | 0.66 | 0.66 |
| 522.50 | 3.39 | 3.39 |
| 436.41 | 1.82 | 1.82 |
| 342.35 | 3.27 | 3.27 |
| 420.41 | 1.60 | 1.60 |
| 436.41 | 1.82 | 1.82 |
| 512.51 | 3.04 | 3.04 |
| 612.65 | 0.63 | 0.63 |
| 552.49 | 3.05 | 3.05 |
| 478.45 | 1.44 | 1.44 |
| 534.56 | 0.99 | 0.99 |
| 522.50 | 3.04 | 3.04 |
| 418.44 | 2.83 | 2.83 |
| 462.45 | 2.37 | 2.37 |
| 574.49 | 1.41 | 1.41 |
| 450.44 | 2.21 | 2.21 |
| 420.41 | 1.60 | 1.60 |
| 462.45 | 2.37 | 2.37 |
| 494.45 | 2.61 | 2.61 |
| 512.51 | 3.39 | 3.39 |
| 546.53 | 3.72 | 3.72 |
| 512.51 | 3.39 | 3.39 |
| 646.65 | 5.40 | 5.40 |
| 450.44 | 2.21 | 2.21 |
| 552.49 | 3.05 | 3.05 |
| 462.45 | 2.17 | 2.17 |
| 646.65 | 5.75 | 5.75 |
| 420.42 | 0.04 | 0.04 |
| 780.78 | 7.76 | 7.76 |
| 578.52 | 1.86 | 1.86 |
| 476.43 | 1.22 | 1.22 |
| 532.57 | 2.75 | 2.75 |
| 450.44 | 2.21 | 2.21 |
| 594.57 | 4.22 | 4.22 |