Assay Report Card

Basic Information

ID: ALA5125569

Type: Functional

Description: Invivo inhibition of SETD2 in NOD SCID mouse xenografted with human KMS-11 cells assessed as reduction in H3K36me3 at 30 mg/kg, po bid administered starting from day 7 to 37 days post inoculation and measured at 12 hr post last dose

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
400.502.822.82