Basic Information
ID: ALA5126058
Type: Binding
Description: Antagonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5126058
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 715.40 | 2.10 | 2.10 |
| 815.52 | 4.41 | 4.41 |
| 775.45 | 2.12 | 2.12 |