Basic Information
ID: ALA5126113
Type: Binding
Description: Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of CDK12 degradation incubated for 15 hrs by immunoblotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: Cereblon/Cyclin-dependent kinase 12(ALA4879535)
Document: ALA5120962
Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of CDK12 degradation incubated for 15 hrs by immunoblotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5126113
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 822.93 | 4.25 | 4.25 |
| 819.92 | 4.86 | 4.86 |
| 808.94 | 4.61 | 4.61 |
| 823.91 | 4.22 | 4.22 |
| 822.93 | 4.25 | 4.25 |
| 808.94 | 4.61 | 4.61 |
| 836.95 | 4.64 | 4.64 |
| 808.90 | 4.85 | 4.85 |