Assay Report Card

Basic Information

ID: ALA5126116

Type: Binding

Description: Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of CDK12 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
793.884.464.46
865.015.425.42
907.096.606.60
765.874.824.82
822.934.254.25
819.924.864.86
817.914.194.19
808.944.614.61
823.914.224.22
822.934.254.25
865.015.425.42
836.954.644.64
935.147.387.38
808.944.614.61
935.147.387.38
907.096.606.60
879.035.825.82
850.985.035.03
822.934.254.25
833.954.954.95
921.126.996.99
836.954.644.64
821.944.784.78
879.035.825.82
836.954.604.60
808.904.854.85
893.066.216.21