ID: ALA5126116
Type: Binding
Description: Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as induction of CDK12 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control
Organism: Homo sapiens
Cell type: MDA-MB-231
Bioactivity
Activity Types for Assay ALA5126116
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
793.88 | 4.46 | 4.46 |
865.01 | 5.42 | 5.42 |
907.09 | 6.60 | 6.60 |
765.87 | 4.82 | 4.82 |
822.93 | 4.25 | 4.25 |
819.92 | 4.86 | 4.86 |
817.91 | 4.19 | 4.19 |
808.94 | 4.61 | 4.61 |
823.91 | 4.22 | 4.22 |
822.93 | 4.25 | 4.25 |
865.01 | 5.42 | 5.42 |
836.95 | 4.64 | 4.64 |
935.14 | 7.38 | 7.38 |
808.94 | 4.61 | 4.61 |
935.14 | 7.38 | 7.38 |
907.09 | 6.60 | 6.60 |
879.03 | 5.82 | 5.82 |
850.98 | 5.03 | 5.03 |
822.93 | 4.25 | 4.25 |
833.95 | 4.95 | 4.95 |
921.12 | 6.99 | 6.99 |
836.95 | 4.64 | 4.64 |
821.94 | 4.78 | 4.78 |
879.03 | 5.82 | 5.82 |
836.95 | 4.60 | 4.60 |
808.90 | 4.85 | 4.85 |
893.06 | 6.21 | 6.21 |