Basic Information
ID: ALA5126117
Type: Binding
Description: Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of CDK13 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: CRBN/CDK13(ALA5169085)
Document: ALA5120962
Protac activity at CRBN/CDK13 in human MDA-MB-231 cells assessed as induction of CDK13 degradation at 1 uM incubated for 15 hrs by immunoblotting analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5126117
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 793.88 | 4.46 | 4.46 |
| 865.01 | 5.42 | 5.42 |
| 907.09 | 6.60 | 6.60 |
| 765.87 | 4.82 | 4.82 |
| 822.93 | 4.25 | 4.25 |
| 819.92 | 4.86 | 4.86 |
| 817.91 | 4.19 | 4.19 |
| 808.94 | 4.61 | 4.61 |
| 823.91 | 4.22 | 4.22 |
| 822.93 | 4.25 | 4.25 |
| 865.01 | 5.42 | 5.42 |
| 836.95 | 4.64 | 4.64 |
| 935.14 | 7.38 | 7.38 |
| 808.94 | 4.61 | 4.61 |
| 935.14 | 7.38 | 7.38 |
| 907.09 | 6.60 | 6.60 |
| 879.03 | 5.82 | 5.82 |
| 850.98 | 5.03 | 5.03 |
| 822.93 | 4.25 | 4.25 |
| 833.95 | 4.95 | 4.95 |
| 921.12 | 6.99 | 6.99 |
| 836.95 | 4.64 | 4.64 |
| 821.94 | 4.78 | 4.78 |
| 879.03 | 5.82 | 5.82 |
| 836.95 | 4.60 | 4.60 |
| 808.90 | 4.85 | 4.85 |
| 893.06 | 6.21 | 6.21 |