Basic Information
ID: ALA5126131
Type: Binding
Description: Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as inhibition of degradation of CDK12 at 500 nM measured after 6 hrs in presence of thalidomide
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: Cereblon/Cyclin-dependent kinase 12(ALA4879535)
Document: ALA5120962
Protac activity at CRBN/CDK12 in human MDA-MB-231 cells assessed as inhibition of degradation of CDK12 at 500 nM measured after 6 hrs in presence of thalidomide: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5126131
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 822.93 | 4.25 | 4.25 |