Basic Information
ID: ALA5126151
Type: Functional
Description: Invivo protac activity at CRBN/CDK12 in human MDA-MB-231 cells xenografted in CB17SCID mouse assessed as degradation of CDK12 in tumor at 50 mg/kg, iv measured after 6 hrs by Western blot analysis
Format: BAO_0000218
Organism: Homo sapiens
Cell type: MDA-MB-231
Target: MDA-MB-231(ALA400)
Document: ALA5120962
Invivo protac activity at CRBN/CDK12 in human MDA-MB-231 cells xenografted in CB17SCID mouse assessed as degradation of CDK12 in tumor at 50 mg/kg, iv measured after 6 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5126151
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 819.92 | 4.86 | 4.86 |