Assay Report Card

Basic Information

ID: ALA5126152

Type: Functional

Description: Invivo protac activity at CRBN/CDK13 in human MDA-MB-231 cells xenografted in CB17SCID mouse assessed as degradation of CDK12 in tumor at 50 mg/kg, iv measured after 6 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
819.924.864.86