Assay Report Card

Basic Information

ID: ALA5126259

Type: Functional

Description: Anti-osteoporosis activity C57/BL6 mouse bone marrow macrophage cells assessed as inhibition of RANKL-induced osteoclastogenesis at 1 uM measured after 5 to 6 days in presence of M-CSF and RNKL by TRAP staining microscopic analysis

Organism: Mus musculus

Strain: C57/BL6

Cell type: BMDM

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
547.626.946.94
425.585.565.56
463.546.076.07
435.536.086.08
425.587.107.10
355.444.394.39
392.465.155.15
476.586.336.33
435.536.086.08
385.473.973.97
398.495.215.21
392.465.155.15
405.505.435.43
495.566.626.62
392.465.155.15
453.977.027.02
419.536.376.37
437.526.516.51
435.536.086.08
433.566.686.68
449.556.386.38
409.495.095.09
397.525.565.56
448.576.416.41
449.556.386.38
437.526.516.51
477.566.166.16
455.516.656.65
437.526.516.51
381.444.484.48
462.606.446.44
434.973.983.98
420.525.775.77
381.444.484.48
395.474.494.49
444.546.246.24
434.545.955.95
449.556.386.38
399.494.414.41
487.537.397.39