Basic Information
ID: ALA5127377
Type: Binding
Description: Inhibition of GST-fused human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5127377
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 245.24 | 0.54 | 0.54 |
| 337.34 | 2.36 | 2.36 |
| 307.31 | 2.35 | 2.35 |
| 287.32 | 1.58 | 1.58 |
| 321.34 | 2.70 | 2.70 |
| 273.29 | 1.24 | 1.24 |
| 315.37 | 2.36 | 2.36 |
| 349.39 | 3.16 | 3.16 |
| 259.26 | 0.85 | 0.85 |
| 321.34 | 2.66 | 2.66 |
| 323.31 | 2.06 | 2.06 |
| 231.25 | 1.32 | 1.32 |
| 399.41 | 4.15 | 4.15 |
| 324.36 | 3.50 | 3.50 |
| 335.36 | 2.97 | 2.97 |
| 335.36 | 2.97 | 2.97 |
| 382.46 | 2.19 | 2.19 |
| 383.41 | 4.02 | 4.02 |
| 403.44 | 2.28 | 2.28 |
| 285.30 | 1.34 | 1.34 |
| 281.29 | 2.76 | 2.76 |
| 293.33 | 2.63 | 2.63 |
| 393.49 | 4.46 | 4.46 |
| 335.36 | 2.97 | 2.97 |
| 405.46 | 2.11 | 2.11 |
| 309.32 | 2.34 | 2.34 |
| 325.30 | 2.49 | 2.49 |
| 341.30 | 2.20 | 2.20 |
| 392.46 | 3.33 | 3.33 |
| 276.32 | 2.00 | 2.00 |
| 321.34 | 2.38 | 2.38 |
| 309.32 | 1.92 | 1.92 |
| 335.36 | 2.79 | 2.79 |
| 408.43 | 2.25 | 2.25 |
| 262.29 | 1.60 | 1.60 |
| 290.34 | 2.34 | 2.34 |
| 321.34 | 2.74 | 2.74 |
| 281.29 | 2.76 | 2.76 |
| 391.47 | 4.48 | 4.48 |
| 295.30 | 2.04 | 2.04 |
| 390.44 | 3.34 | 3.34 |
| 314.35 | 0.58 | 0.58 |
| 304.37 | 2.73 | 2.73 |
| 321.34 | 2.40 | 2.40 |
| 309.32 | 2.34 | 2.34 |
| 417.47 | 2.53 | 2.53 |
| 325.30 | 2.49 | 2.49 |
| 309.32 | 2.35 | 2.35 |
| 407.47 | 2.09 | 2.09 |
| 245.24 | 0.46 | 0.46 |
| 299.33 | 1.73 | 1.73 |
| 391.43 | 1.76 | 1.76 |
| 231.21 | 0.20 | 0.20 |
| 293.33 | 2.63 | 2.63 |
| 393.45 | 1.75 | 1.75 |
| 290.34 | 2.39 | 2.39 |
| 308.30 | 1.75 | 1.75 |
| 301.30 | 0.57 | 0.57 |
| 319.36 | 2.95 | 2.95 |
| 305.34 | 2.56 | 2.56 |
| 393.44 | 3.92 | 3.92 |