Basic Information
ID: ALA5128305
Type: Binding
Description: Inhibition of LPS-stimulated TLR4 activation in HEK-Blue-hTLR4 cells assessed as reduction in SEAP release preincubated for 15 mins followed by LPS stimulation and measured after 16 hrs by microplate reader assay
Organism: Homo sapiens
Cell type: HEK-Blue hTLR4
Activity Charts
Bioactivity
Activity Types for Assay ALA5128305
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 854.13 | 9.02 | 9.02 |
| 838.09 | 8.41 | 8.41 |
| 800.04 | 7.69 | 7.69 |
| 880.17 | 9.58 | 9.58 |
| 876.14 | 9.13 | 9.13 |