Basic Information
ID: ALA5128697
Type: Binding
Description: Inhibition of ABCG2 (unknown origin) expressed in human HEK293 cells mediated mitoxantrone efflux assessed as intracellular mitoxantrone level preincubated with mitoxantrone followed by compound addition and measured upto 60 mins by FACSflow cytometry analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5128697
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 670.86 | 3.09 | 3.09 |
| 567.80 | 4.75 | 4.75 |