Basic Information
ID: ALA5128699
Type: Binding
Description: Inhibition of human ABCG2 expressed in human HEK293 cells membrane vesicles mediated transport of 3[H]-MTX for 2 mins using [3H]-methotrexate as substrate by rapid filtration technique
Format: BAO_0000249
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Membrane vesicle
Target: ATP-binding cassette sub-family G member 2(ALA5393)
Document: ALA5126555
Inhibition of human ABCG2 expressed in human HEK293 cells membrane vesicles mediated transport of 3[H]-MTX for 2 mins using [3H]-methotrexate as substrate by rapid filtration technique: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5128699
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.37 | 3.52 | 3.52 |
| 359.45 | 2.99 | 2.99 |
| 383.38 | 2.88 | 2.88 |
| 345.42 | 2.90 | 2.90 |