Basic Information
ID: ALA5128979
Type: Binding
Description: Inhibition of N-terminal His-tagged SARS-CoV2 nsp3 Mac1 (205 to 379 residues) expressed in Escherichia coli BL21 (DE3) using ARTK(Bio)QTARK(Aoa-EADP)S peptide as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hrs by Alphascreen assay
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5128979
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 234.26 | 1.48 | 1.48 |
| 277.33 | 3.09 | 3.09 |
| 321.34 | 2.55 | 2.55 |
| 192.18 | 0.45 | 0.45 |
| 232.24 | 0.87 | 0.87 |
| 260.30 | 1.71 | 1.71 |
| 361.28 | -0.18 | -0.18 |
| 274.32 | 1.74 | 1.74 |
| 232.24 | 0.71 | 0.71 |
| 218.22 | 0.48 | 0.48 |
| 262.31 | 1.96 | 1.96 |
| 335.37 | 2.64 | 2.64 |
| 232.24 | 1.01 | 1.01 |
| 360.29 | 1.26 | 1.26 |
| 232.24 | 0.87 | 0.87 |
| 274.32 | 1.74 | 1.74 |
| 375.31 | -0.09 | -0.09 |
| 276.34 | 2.35 | 2.35 |
| 220.25 | 1.90 | 1.90 |
| 246.27 | 1.10 | 1.10 |
| 232.24 | 0.57 | 0.57 |
| 248.29 | 1.87 | 1.87 |
| 232.24 | 1.01 | 1.01 |
| 246.27 | 1.62 | 1.62 |
| 220.23 | 0.87 | 0.87 |
| 218.22 | 0.62 | 0.62 |
| 246.27 | 1.26 | 1.26 |
| 374.32 | 1.35 | 1.35 |
| 246.27 | 1.26 | 1.26 |
| 246.27 | 0.96 | 0.96 |