Assay Report Card

Basic Information

ID: ALA5128979

Type: Binding

Description: Inhibition of N-terminal His-tagged SARS-CoV2 nsp3 Mac1 (205 to 379 residues) expressed in Escherichia coli BL21 (DE3) using ARTK(Bio)QTARK(Aoa-EADP)S peptide as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hrs by Alphascreen assay

Organism: Severe acute respiratory syndrome coronavirus 2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
234.261.481.48
277.333.093.09
321.342.552.55
192.180.450.45
232.240.870.87
260.301.711.71
361.28-0.18-0.18
274.321.741.74
232.240.710.71
218.220.480.48
262.311.961.96
335.372.642.64
232.241.011.01
360.291.261.26
232.240.870.87
274.321.741.74
375.31-0.09-0.09
276.342.352.35
220.251.901.90
246.271.101.10
232.240.570.57
248.291.871.87
232.241.011.01
246.271.621.62
220.230.870.87
218.220.620.62
246.271.261.26
374.321.351.35
246.271.261.26
246.270.960.96