Assay Report Card

Basic Information

ID: ALA5128982

Type: Binding

Description: Inhibition of N-terminal His-tagged SARS-CoV2 nsp3 Mac1 (205 to 379 residues) expressed in Escherichia coli BL21 (DE3) assessed as thermal shift at 300 uM in the presence of ADP-ribose by differential scanning fluorimetry analysis

Organism: Severe acute respiratory syndrome coronavirus 2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
559.32-3.28-3.28
321.342.552.55
260.301.711.71
335.372.642.64
246.271.621.62
246.271.261.26
246.271.261.26