Assay Report Card

Basic Information

ID: ALA5128984

Type: Binding

Description: Inhibition of N-terminal His-tagged SARS-CoV2 nsp3 Mac1 (205 to 379 residues) expressed in Escherichia coli BL21 (DE3) preincubated with enzyme for 30 mins followed by addition of mono-ADP ribosylated substrate and measured after 30 mins in the presence of NudF ADP-ribose pyrophosphate by ADPr Glo assay

Organism: Severe acute respiratory syndrome coronavirus 2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
321.342.552.55
246.271.261.26