Basic Information
ID: ALA5129148
Type: Binding
Description: Inhibition of p53 in human MOLT-4 cells assessed as suppression of gamma-irradiation-induced decrease in cell viability at 20 to 100 uM preincubated for 1 hr followed by 10 Gy 137Cs gamma-ray exposure and measured after 27 hrs by erythrosin B staining based dye exclusion assay
Organism: Homo sapiens
Cell type: MOLT-4
Activity Charts
Bioactivity
Activity Types for Assay ALA5129148
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.41 | 2.84 | 2.84 |
| 393.40 | 3.27 | 3.27 |
| 350.37 | 2.97 | 2.97 |
| 366.37 | 2.67 | 2.67 |
| 394.38 | 3.48 | 3.48 |
| 421.45 | 3.75 | 3.75 |
| 393.40 | 3.27 | 3.27 |
| 417.43 | 2.75 | 2.75 |
| 351.36 | 2.36 | 2.36 |
| 407.42 | 3.66 | 3.66 |
| 363.37 | 3.26 | 3.26 |
| 393.40 | 3.27 | 3.27 |
| 379.41 | 3.58 | 3.58 |
| 383.83 | 4.23 | 4.23 |
| 379.37 | 2.97 | 2.97 |
| 393.40 | 3.27 | 3.27 |
| 393.40 | 3.27 | 3.27 |
| 451.43 | 2.82 | 2.82 |
| 406.44 | 3.19 | 3.19 |