Assay Report Card

Basic Information

ID: ALA5129507

Type: Functional

Description: Antiviral activity against Hepatitis B virus infected in human HepG2 cells expressing NTCP assessed as inhibition of viral entry by measuring intracellular HBV DNA at 1 uM preincubated with compound for 2 hrs followed by viral infection and measured after 3 hrs by qPCR analysis relative to control

Organism: Hepatitis B virus

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1202.63
1175.57
1232.66
1219.62
1219.62
1233.60
1175.57
1217.65
1160.60
1205.59
1233.60
1217.65
1233.60
1217.65
1205.59
1175.57
1219.62
1251.67
1205.59
1232.66
1232.66
1251.67
1217.65
1251.67