Basic Information
ID: ALA5129522
Type: Functional
Description: Antiproliferative activity against EML4-ALK positive human NCI-H2228 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H2228
Target: NCI-H2228(ALA1075536)
Document: ALA5126595
Antiproliferative activity against EML4-ALK positive human NCI-H2228 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5129522
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 558.15 | 6.36 | 6.36 |
| 599.12 | 3.53 | 3.53 |
| 583.12 | 4.56 | 4.56 |
| 569.09 | 4.17 | 4.17 |
| 514.01 | 4.48 | 4.48 |
| 572.12 | 4.97 | 4.97 |
| 477.96 | 4.47 | 4.47 |
| 486.94 | 4.48 | 4.48 |
| 478.94 | 4.94 | 4.94 |
| 556.05 | 4.25 | 4.25 |
| 570.08 | 4.38 | 4.38 |
| 532.05 | 5.64 | 5.64 |
| 500.97 | 4.57 | 4.57 |
| 492.97 | 5.20 | 5.20 |
| 554.08 | 5.40 | 5.40 |
| 515.00 | 4.96 | 4.96 |
| 519.99 | 4.24 | 4.24 |
| 542.02 | 3.60 | 3.60 |
| 570.08 | 4.38 | 4.38 |
| 464.91 | 4.55 | 4.55 |
| 518.02 | 5.39 | 5.39 |
| 503.99 | 5.00 | 5.00 |
| 540.05 | 5.01 | 5.01 |
| 534.02 | 4.36 | 4.36 |
| 547.06 | 4.54 | 4.54 |
| 563.06 | 3.52 | 3.52 |
| 534.02 | 4.36 | 4.36 |
| 505.97 | 3.58 | 3.58 |
| 478.94 | 4.81 | 4.81 |
| 530.01 | 3.50 | 3.50 |
| 568.10 | 5.65 | 5.65 |
| 533.04 | 4.15 | 4.15 |
| 506.99 | 5.59 | 5.59 |
| 464.91 | 5.15 | 5.15 |