Basic Information
ID: ALA5129610
Type: Binding
Description: Inhibition of NFATC activity in HEK293T cells at 5 to 50 uM preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293T
Target: Nuclear factor of activated T-cells cytoplasmic 1(ALA3876)
Document: ALA5126596
Inhibition of NFATC activity in HEK293T cells at 5 to 50 uM preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5129610
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.57 | 3.10 | 3.10 |
| 498.41 | 4.53 | 4.53 |
| 388.47 | 2.67 | 2.67 |
| 371.42 | 1.94 | 1.94 |
| 382.44 | 2.61 | 2.61 |
| 360.46 | 3.20 | 3.20 |
| 354.43 | 3.14 | 3.14 |
| 343.41 | 2.47 | 2.47 |
| 388.47 | 2.67 | 2.67 |
| 360.44 | 2.02 | 2.02 |
| 352.44 | 1.45 | 1.45 |