Basic Information
ID: ALA5129611
Type: Binding
Description: Inhibition of NFATC activity in HEK293T cells at 50 uM preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293T
Target: Nuclear factor of activated T-cells cytoplasmic 1(ALA3876)
Document: ALA5126596
Inhibition of NFATC activity in HEK293T cells at 50 uM preincubated for 2 hrs followed by ionomycin/phorbol 12-myristate 13-acetate stimulation and measured after 4 hrs by luciferase reporter assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5129611
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.46 | 0.41 | 0.41 |
| 421.43 | 0.91 | 0.91 |
| 420.45 | 0.46 | 0.46 |
| 440.53 | 2.71 | 2.71 |
| 419.46 | 0.98 | 0.98 |
| 324.43 | 1.98 | 1.98 |
| 442.45 | 0.97 | 0.97 |
| 332.43 | 2.55 | 2.55 |
| 447.49 | 1.63 | 1.63 |
| 352.44 | 1.45 | 1.45 |