Basic Information
ID: ALA5129616
Type: Binding
Description: Inhibition of NFATC activity in human CD4+ T cells assessed as reduction of IFN gamma secretion preincubated for 2 hrs followed by anti-CD3/CD28 stimulation and measured after 48 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CD4+ve Th
Target: Nuclear factor of activated T-cells cytoplasmic 1(ALA3876)
Document: ALA5126596
Inhibition of NFATC activity in human CD4+ T cells assessed as reduction of IFN gamma secretion preincubated for 2 hrs followed by anti-CD3/CD28 stimulation and measured after 48 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5129616
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.41 | 4.53 | 4.53 |
| 360.46 | 3.20 | 3.20 |
| 343.41 | 2.47 | 2.47 |