Assay Report Card

Basic Information

ID: ALA5129853

Type: Functional

Description: Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 1 nmol/Kg, IT(Intratracheal) measured after 30 mins by Konzett-Roessler methodology relative to control

Organism: Cavia porcellus

Strain: Dunkin-Hartley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
764.884.724.72
292.340.630.63
490.563.613.61