Basic Information
ID: ALA5129862
Type: Functional
Description: Invivo antagonist activity at muscarinic M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine induced bronchoconstriction at 1 nmol/Kg, IT(Intratracheal) measured after 24 hr in presence of ICI-118551 by Konzett-Roessler methodology relative to control
Organism: Cavia porcellus
Strain: Dunkin-Hartley
Activity Charts
Bioactivity
Activity Types for Assay ALA5129862
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 764.88 | 4.72 | 4.72 |
| 750.85 | 5.58 | 5.58 |
| 751.84 | 4.97 | 4.97 |