Basic Information
ID: ALA5130014
Type: Binding
Description: Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation at 10 uM preincubated with compound for 1 hrs followed by CpGB addition and measured next day by SEAP-based spectrophotometry assay
Organism: Homo sapiens
Cell type: HEK-Blue hTLR9
Activity Charts
Bioactivity
Activity Types for Assay ALA5130014
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.30 | 2.60 | 2.60 |
| 303.16 | 3.77 | 3.77 |
| 333.19 | 3.78 | 3.78 |
| 239.28 | 2.59 | 2.59 |
| 273.13 | 3.76 | 3.76 |