Basic Information
ID: ALA5130018
Type: Binding
Description: Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation at 30 uM preincubated with compound for 1 hrs followed by CL264 addition and measured next day by SEAP-based spectrophotometry assay
Organism: Homo sapiens
Cell type: HEK-Blue hTLR7
Activity Charts
Bioactivity
Activity Types for Assay ALA5130018
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 269.30 | 2.60 | 2.60 |
| 239.28 | 2.59 | 2.59 |