Assay Report Card

Basic Information

ID: ALA5130020

Type: Binding

Description: Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation at 20 uM preincubated with compound for 1 hrs followed by CL264 addition and measured next day by SEAP-based spectrophotometry assay

Organism: Homo sapiens

Cell type: HEK-Blue hTLR7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
565.766.256.25