Assay Report Card

Basic Information

ID: ALA5130021

Type: Binding

Description: Antagonist activity at TLR9 in human pDCs inhibition of CpGB-induced NFkappaB activation by measuring IFN-alpha levels preincubated with compound for 1 hrs followed by CpGB addition and measured after 18 hrs by ELISA analysis

Organism: Homo sapiens

Cell type: Plasmacytoid dendritic cell

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
380.493.553.55