Basic Information
ID: ALA5130022
Type: Binding
Description: Antagonist activity at human TLR8 expressed in HEK-blue hTLR8 cells assessed as inhibition of CL075-induced NFkappaB activation preincubated with compound for 1 hrs followed by CL075 addition and measured next day by SEAP-based spectrophotometry assay
Organism: Homo sapiens
Cell type: HEK-Blue hTLR8
Activity Charts
Bioactivity
Activity Types for Assay ALA5130022
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.49 | 3.55 | 3.55 |
| 380.49 | 3.92 | 3.92 |