Assay Report Card

Basic Information

ID: ALA5130037

Type: Functional

Description: In vivo antagonist activity at TLR9 in C57BL/6 mouse assessed as decrease in IRF7 mRNA expression in peritoneal fluid at 10 mg/kg, po pretreated for 1 hr followed by CpGA/CpGB administration and measured after 18 hrs by qRT-PCR analysis

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
380.493.553.55