Basic Information
ID: ALA5130043
Type: Toxicity
Description: Inhibition of hERG expressed in CHO cells at 3 uM at -80 mV holding potential assessed as current block incubated for 3 mins by Qpatch clamp method relative to control
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5130043
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.53 | 3.79 | 3.79 |
| 489.53 | 3.65 | 3.65 |
| 491.50 | 3.68 | 3.68 |
| 572.54 | 4.67 | 4.67 |
| 504.54 | 3.65 | 3.65 |
| 546.62 | 4.01 | 4.01 |
| 601.70 | 4.46 | 4.46 |
| 573.65 | 3.39 | 3.39 |
| 509.95 | 4.29 | 4.29 |
| 572.66 | 4.45 | 4.45 |
| 586.60 | 4.20 | 4.20 |
| 536.58 | 5.53 | 5.53 |
| 571.59 | 3.23 | 3.23 |
| 533.58 | 3.76 | 3.76 |
| 556.57 | 3.68 | 3.68 |
| 544.61 | 3.63 | 3.63 |
| 586.60 | 3.56 | 3.56 |
| 500.55 | 4.69 | 4.69 |
| 560.99 | 4.84 | 4.84 |
| 587.68 | 4.12 | 4.12 |
| 526.55 | 4.19 | 4.19 |
| 589.65 | 3.49 | 3.49 |
| 586.60 | 4.01 | 4.01 |
| 588.66 | 4.54 | 4.54 |
| 575.62 | 3.00 | 3.00 |
| 475.50 | 3.64 | 3.64 |
| 542.55 | 3.48 | 3.48 |
| 580.61 | 4.02 | 4.02 |
| 518.57 | 3.96 | 3.96 |
| 508.57 | 3.46 | 3.46 |
| 610.54 | 5.09 | 5.09 |
| 607.64 | 3.63 | 3.63 |
| 528.55 | 4.47 | 4.47 |
| 570.60 | 4.94 | 4.94 |
| 582.63 | 3.05 | 3.05 |
| 538.53 | 3.50 | 3.50 |
| 576.61 | 3.43 | 3.43 |
| 607.64 | 3.63 | 3.63 |
| 519.51 | 3.34 | 3.34 |