Basic Information
ID: ALA5130156
Type: ADME
Description: Inhibition of human CYP11B2 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoimager analysis
Organism: Homo sapiens
Cell type: V79 MZh
Activity Charts
Bioactivity
Activity Types for Assay ALA5130156
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 227.24 | 2.43 | 2.43 |
| 351.38 | 3.38 | 3.38 |
| 452.31 | 3.88 | 3.88 |
| 351.38 | 3.38 | 3.38 |
| 347.42 | 3.26 | 3.26 |
| 373.42 | 3.12 | 3.12 |
| 402.28 | 4.55 | 4.55 |
| 347.42 | 3.55 | 3.55 |
| 358.40 | 3.11 | 3.11 |
| 467.50 | 4.92 | 4.92 |
| 351.38 | 3.38 | 3.38 |
| 467.50 | 4.92 | 4.92 |
| 373.42 | 3.12 | 3.12 |
| 373.42 | 3.12 | 3.12 |
| 352.37 | 2.77 | 2.77 |
| 479.54 | 4.79 | 4.79 |
| 358.40 | 3.11 | 3.11 |
| 348.41 | 2.94 | 2.94 |
| 348.41 | 2.82 | 2.82 |
| 347.42 | 3.55 | 3.55 |
| 455.54 | 4.84 | 4.84 |
| 347.42 | 3.55 | 3.55 |
| 333.39 | 3.24 | 3.24 |
| 439.48 | 4.38 | 4.38 |
| 367.84 | 3.89 | 3.89 |
| 363.42 | 3.25 | 3.25 |
| 474.52 | 4.65 | 4.65 |
| 378.39 | 3.15 | 3.15 |
| 517.51 | 5.80 | 5.80 |
| 378.39 | 3.15 | 3.15 |
| 367.84 | 3.89 | 3.89 |
| 335.37 | 2.03 | 2.03 |
| 372.43 | 3.72 | 3.72 |
| 372.43 | 3.72 | 3.72 |
| 363.42 | 3.25 | 3.25 |
| 363.42 | 3.25 | 3.25 |
| 474.52 | 4.65 | 4.65 |