Basic Information
ID: ALA5130303
Type: Binding
Description: Inhibition of human recombinant AKR1C1 transfected in Escherichia coli BL21 (DE3) pLysS competent cells assessed as inhibition of NADP+ dependent oxidation of S-tetralol using S-tetralol as substrate incubated for 10 mins by fluorescence microplate reader assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5130303
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.50 | 2.49 | 2.49 |
| 373.41 | 2.89 | 2.89 |
| 333.34 | 2.14 | 2.14 |
| 335.39 | 0.94 | 0.94 |
| 371.46 | 2.97 | 2.97 |