Basic Information
ID: ALA5130388
Type: Functional
Description: Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as reduction in cAMP accumulation by measuring maximum efficacy incubated for 2 hrs under dark condition by LANCE cAMP assay relative to GLP1
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Glucagon-like peptide 1 receptor(ALA1784)
Document: ALA5126621
Agonist activity at human GLP-1R expressed in CHO cells coexpressing beta-arrestin-2 assessed as reduction in cAMP accumulation by measuring maximum efficacy incubated for 2 hrs under dark condition by LANCE cAMP assay relative to GLP1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5130388
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 4186.64 | ||
| 3235.66 | ||
| 3251.66 | ||
| 3265.68 | ||
| 4067.52 | ||
| 3353.79 | ||
| 3251.66 | ||
| 3265.68 | ||
| 3281.68 | ||
| 3307.72 | ||
| 3267.66 | ||
| 3235.66 | ||
| 3219.66 | ||
| 4224.73 | ||
| 3281.68 | ||
| 3281.68 | ||
| 3249.68 | ||
| 3251.66 | ||
| 3235.66 | ||
| 3289.79 | ||
| 3265.68 |