Basic Information
ID: ALA5130504
Type: Binding
Description: Irreversible inhibition of MPO (unknown origin) assessed as fold shift in EC50 incubated with compound followed by drug washing and later treated with H2O2 for enzyme reactivation by chemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5130504
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.78 | 1.72 | 1.72 |
| 252.30 | 0.96 | 0.96 |
| 334.83 | 3.11 | 3.11 |
| 320.81 | 2.55 | 2.55 |
| 362.84 | 2.72 | 2.72 |
| 335.82 | 2.50 | 2.50 |
| 329.43 | 2.33 | 2.33 |
| 328.44 | 2.93 | 2.93 |
| 326.43 | 2.64 | 2.64 |
| 334.83 | 2.81 | 2.81 |
| 390.94 | 4.22 | 4.22 |
| 362.46 | 3.48 | 3.48 |
| 348.86 | 3.37 | 3.37 |
| 334.83 | 3.11 | 3.11 |
| 276.30 | 1.97 | 1.97 |
| 334.83 | 2.81 | 2.81 |
| 334.83 | 2.81 | 2.81 |