Basic Information
ID: ALA5130518
Type: ADME
Description: Competitive inhibition of human recombinant CYP3A4 using coumarin as substrate preincubated with enzyme for 10 mins followed by NADPH addition and measured after 20 to 50 mins by fluorescence based method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5130518
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.83 | 3.11 | 3.11 |
| 320.81 | 2.55 | 2.55 |
| 335.82 | 2.50 | 2.50 |
| 334.83 | 2.81 | 2.81 |