Basic Information
ID: ALA5130546
Type: Binding
Description: Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular calcium accumulation at 10 uM preincubated with compound followed by capsaicin addition and measured at 180 sec by fluorescence based microplate reader analysis relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5130546
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.90 | 4.39 | 4.39 |
| 356.82 | 2.97 | 2.97 |
| 335.41 | 3.23 | 3.23 |
| 336.40 | 2.62 | 2.62 |
| 352.40 | 2.32 | 2.32 |
| 424.81 | 3.98 | 3.98 |
| 370.84 | 2.96 | 2.96 |
| 401.27 | 3.07 | 3.07 |
| 356.82 | 2.97 | 2.97 |
| 336.40 | 2.62 | 2.62 |
| 390.27 | 4.22 | 4.22 |
| 356.82 | 2.97 | 2.97 |
| 336.40 | 2.62 | 2.62 |
| 350.43 | 2.62 | 2.62 |
| 336.40 | 2.62 | 2.62 |
| 355.83 | 3.57 | 3.57 |
| 356.82 | 2.97 | 2.97 |
| 390.37 | 3.33 | 3.33 |