Basic Information
ID: ALA5131025
Type: Binding
Description: Inhibition of human His-Sumo-tagged PAD4 (A2 to P663 residues) expressed in Escherichia coli BL21 (DE3) cells using BAEE as substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5131025
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.69 | 4.30 | 4.30 |
| 640.79 | 4.27 | 4.27 |
| 752.90 | 4.24 | 4.24 |
| 618.76 | 2.52 | 2.52 |
| 661.81 | 5.08 | 5.08 |
| 613.72 | 3.82 | 3.82 |