Assay Report Card

Basic Information

ID: ALA5131050

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in pyroptosis at 20 uM pretreated for 0.5 hrs followed by stimulation with nigericin for 1 hr by fluorescent microscopic analysis

Organism: Mus musculus

Cell type: J774.A1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
388.504.164.16