Basic Information
ID: ALA5131233
Type: Binding
Description: Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Jurkat
Target: Tyrosine-protein kinase TYK2(ALA3553)
Document: ALA5126671
Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5131233
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.47 | 1.73 | 1.73 |
| 558.61 | 3.31 | 3.31 |
| 518.55 | 2.68 | 2.68 |
| 566.68 | 2.85 | 2.85 |
| 576.67 | 4.03 | 4.03 |
| 587.66 | 3.81 | 3.81 |
| 512.57 | 2.35 | 2.35 |
| 562.65 | 3.67 | 3.67 |
| 507.53 | 1.68 | 1.68 |
| 506.54 | 2.29 | 2.29 |
| 586.67 | 3.96 | 3.96 |
| 518.55 | 2.43 | 2.43 |
| 574.66 | 3.86 | 3.86 |
| 534.59 | 2.94 | 2.94 |
| 520.56 | 2.55 | 2.55 |
| 578.62 | 3.56 | 3.56 |
| 578.64 | 3.02 | 3.02 |
| 587.63 | 4.35 | 4.35 |
| 578.67 | 3.34 | 3.34 |
| 560.63 | 3.43 | 3.43 |
| 561.62 | 2.82 | 2.82 |
| 578.64 | 3.02 | 3.02 |
| 597.65 | 3.32 | 3.32 |
| 596.63 | 3.16 | 3.16 |
| 518.55 | 2.43 | 2.43 |
| 596.68 | 2.97 | 2.97 |
| 518.55 | 2.43 | 2.43 |
| 564.65 | 3.43 | 3.43 |
| 569.64 | 4.22 | 4.22 |