Basic Information
ID: ALA5131257
Type: Binding
Description: Selectivity ratio of IC50 for JAK2 in platelet cells (unknown origin) assessed as reduction in EPO stimulated STAT3 phosphorylation to IC50 for inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA5126671
Selectivity ratio of IC50 for JAK2 in platelet cells (unknown origin) assessed as reduction in EPO stimulated STAT3 phosphorylation to IC50 for inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5131257
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.64 | 3.02 | 3.02 |