Basic Information
ID: ALA5131997
Type: Binding
Description: Allosteric inverse agonist activity at C-terminal His-tagged RORgammat LBD (265 to 507 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as N-terminal biotinylated SRC1 box2 coactivator peptide recruitment by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5131997
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.80 | 5.76 | 5.76 |
| 461.83 | 6.32 | 6.32 |
| 458.82 | 6.88 | 6.88 |
| 480.80 | 6.43 | 6.43 |
| 462.81 | 6.29 | 6.29 |
| 463.80 | 5.68 | 5.68 |
| 476.84 | 6.30 | 6.30 |
| 479.82 | 6.46 | 6.46 |
| 462.81 | 6.29 | 6.29 |
| 475.85 | 6.34 | 6.34 |
| 458.82 | 6.88 | 6.88 |
| 476.84 | 6.59 | 6.59 |
| 478.88 | 7.00 | 7.00 |