Basic Information
ID: ALA5132100
Type: Functional
Description: Agonist activity at GPR88 (unknown origin) expressed in CHO cells coexpressing PPLS-HA assessed as reduction in forskolin-stimulated cAMP production and measured after 90 mins by Lance TR-FRET cAMP assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Probable G-protein coupled receptor 88(ALA3399910)
Document: ALA5131380
Agonist activity at GPR88 (unknown origin) expressed in CHO cells coexpressing PPLS-HA assessed as reduction in forskolin-stimulated cAMP production and measured after 90 mins by Lance TR-FRET cAMP assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5132100
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.52 | 4.42 | 4.42 |
| 459.59 | 4.39 | 4.39 |
| 396.53 | 4.21 | 4.21 |
| 435.57 | 5.40 | 5.40 |
| 421.54 | 5.20 | 5.20 |
| 436.56 | 4.67 | 4.67 |
| 418.54 | 4.50 | 4.50 |
| 434.54 | 3.61 | 3.61 |
| 432.52 | 3.93 | 3.93 |
| 450.58 | 4.25 | 4.25 |
| 419.53 | 4.76 | 4.76 |
| 477.61 | 4.11 | 4.11 |
| 432.57 | 4.74 | 4.74 |
| 480.61 | 5.79 | 5.79 |
| 446.60 | 5.24 | 5.24 |
| 476.58 | 4.18 | 4.18 |
| 444.58 | 5.00 | 5.00 |
| 418.54 | 4.20 | 4.20 |
| 404.51 | 4.12 | 4.12 |
| 446.55 | 4.32 | 4.32 |
| 447.58 | 3.84 | 3.84 |
| 404.51 | 4.19 | 4.19 |
| 461.61 | 4.18 | 4.18 |
| 420.56 | 4.75 | 4.75 |
| 486.66 | 6.17 | 6.17 |
| 446.60 | 5.07 | 5.07 |
| 433.56 | 3.58 | 3.58 |
| 448.57 | 4.26 | 4.26 |
| 418.54 | 4.43 | 4.43 |
| 432.57 | 4.68 | 4.68 |
| 488.68 | 6.24 | 6.24 |
| 476.58 | 4.29 | 4.29 |
| 421.55 | 4.22 | 4.22 |
| 475.59 | 3.82 | 3.82 |
| 404.51 | 4.12 | 4.12 |
| 435.57 | 5.40 | 5.40 |
| 460.62 | 5.42 | 5.42 |
| 461.57 | 3.48 | 3.48 |
| 447.54 | 3.22 | 3.22 |
| 448.57 | 4.52 | 4.52 |