Basic Information
ID: ALA5132797
Type: Binding
Description: Inhibition of FLAG-tagged full-length human recombinant DYRK1A (127 to 485 residues) expressed in Escherichia coli assessed as reduction in substrate peptide phosphorylation at 32 uM using DYRKtide peptide as substrate incubated for 45 mins in presence of ATP by Kinase-Glo Luminescent kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5132797
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.54 | ||
| 359.52 | 4.78 | 4.78 |
| 533.75 | ||
| 471.68 | ||
| 409.61 | ||
| 405.69 | ||
| 333.48 | 4.24 | 4.24 |
| 281.36 | 2.28 | 2.28 |
| 522.01 | ||
| 349.55 | ||
| 431.70 | ||
| 389.62 | ||
| 389.62 |