Basic Information
ID: ALA5133047
Type: Functional
Description: Antagonist activity against human CysLT1 expressed in CHO cells assessed as inhibition of LTD4 induced cytosolic Calcium ion mobilization measured after 75 mins by Fluo4 dye based fluorimetric microplate reader assay relative to control
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5133047
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 335.45 | 5.43 | 5.43 |
| 307.39 | 4.99 | 4.99 |
| 279.30 | 3.51 | 3.51 |
| 321.42 | 5.38 | 5.38 |
| 293.32 | 3.60 | 3.60 |
| 321.42 | 5.24 | 5.24 |
| 265.31 | 3.31 | 3.31 |
| 295.29 | 3.22 | 3.22 |
| 265.31 | 3.31 | 3.31 |
| 281.31 | 3.01 | 3.01 |
| 293.37 | 4.60 | 4.60 |
| 293.37 | 4.60 | 4.60 |
| 307.39 | 4.99 | 4.99 |
| 309.32 | 3.31 | 3.31 |
| 279.30 | 3.51 | 3.51 |
| 293.32 | 3.60 | 3.60 |