Basic Information
ID: ALA5133214
Type: Binding
Description: Selectivity ratio of IC50 for inhibition of human muscarinic acetylcholine M2 receptor to IC50 for inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentration by calcium mobilization assay
Activity Charts
Bioactivity
Activity Types for Assay ALA5133214
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.52 | 4.50 | 4.50 |
| 428.53 | 4.36 | 4.36 |
| 444.98 | 4.88 | 4.88 |
| 392.55 | 4.08 | 4.08 |
| 449.60 | 4.04 | 4.04 |
| 446.60 | 3.97 | 3.97 |
| 448.53 | 4.50 | 4.50 |