Basic Information
ID: ALA5134955
Type: Binding
Description: Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay
Organism: Homo sapiens
Cell type: 1321N1
Activity Charts
Bioactivity
Activity Types for Assay ALA5134955
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.50 | 4.26 | 4.26 |
| 435.43 | 5.60 | 5.60 |